SkinCeuticals A.G.E. Interrupter Advanced is a next-generation corrective cream that helps reverse the visible signs of ageing driven by collagen decline and glycation — the process where excess sugars bind to collagen and elastin, forming damaging by-products (A.G.E.s) that lead to wrinkles, laxity and dullness. Backed by over 15 years of glycation research, it is clinically shown to smooth five distinct wrinkle types in the zones most often targeted for aesthetic procedures.
Why does our founder Becci love this? As a registered aesthetics nurse with over 20 years' experience, she rates it for tackling glycation — one of the harder-to-treat drivers of ageing — in a cream elegant enough to wear every day.
This potent formula pairs 18% concentrated Proxylane (20% more active than the original A.G.E. Interrupter) with a 4.25% wild fruit flavonoid blend of blueberry and pomegranate extracts, plus 0.1% glycyrrhetinic acid from liquorice root. Together they help correct existing damage and defend against new A.G.E. formation, restoring firmness and radiance while delivering a rich, satin finish. If you have been searching for the best anti-wrinkle cream for mature or glycation-prone skin, this is it.
Visible Results Users Love
- Global fine lines reduced by 14.1%
- Targeted deep wrinkles reduced by 7.9%
- Smooths five wrinkle types: forehead lines, frown lines, crow's feet, nasolabial folds and marionette lines
- Skin feels firmer and looks more radiant
- 24-hour hydration in a luxurious, satin finish
Why This Beats a Standard Moisturiser
Most creams simply hydrate the surface. A.G.E. Interrupter Advanced targets the underlying glycation process itself — correcting collagen damage and helping to block new A.G.E.s from forming — so skin looks firmer and more even over time, not just softer for the day.
Best For
Anyone concerned with lines, wrinkles, loss of firmness and dullness — especially mature and glycation-prone skin. Suitable for dry, normal, combination and sensitive skin across all skin tones.
Size: 48ml
