PCA Skin Intensive Age Refining Treatment

This is a nighttime retinol treatment that targets the visible signs of ageing including fine lines, wrinkles, uneven skin tone and loss of firmness. It uses 0.5% pure retinol combined with retinopeptide and orange stem cell extract technology, all delivered through PCA Skin's patented OmniSome system which carries ingredients deeper into the skin over a 10-hour time-release period.

For those with oily, combination or normal skin concerned with ageing, this is one of the most advanced retinol treatments available. The OmniSome delivery system — originally used in pharmaceuticals — sets it apart from standard retinol formulas by delivering active ingredients deeper and more steadily into the skin. It's an excellent choice for anyone wanting visible anti-ageing results with minimal irritation.

Start by applying a pea-sized amount in the evening twice per week. As your skin builds tolerance, gradually increase to every other night, then advance to nightly use as tolerated. Always follow with a moisturiser and apply broad-spectrum SPF the following morning.

OmniSome is PCA Skin's patented delivery system that was originally used in pharmaceuticals and is entirely new to skincare. It stabilises and carries a unique blend of active ingredients deeper into the skin over a 10-hour time-release period, providing superior and longer-lasting results compared to conventional retinol formulations.

This formula is designed to minimise irritation through its stabilised retinol and soothing ingredients including panthenol and oat kernel extract. Some mild irritation when first starting is normal and is not a sign of a negative reaction — it typically subsides as your skin adjusts. Starting with twice-weekly application and gradually increasing frequency will help your skin build tolerance comfortably.

You can use vitamin C in the morning and this retinol treatment in the evening as part of a well-rounded routine. However, it's best to avoid layering other strong actives such as AHAs or BHAs at the same time as retinol to reduce the risk of irritation. If you're unsure, consult a skincare professional for personalised guidance.

PCA Skin recommends this treatment for oily, combination and normal skin types concerned with ageing. If you have particularly sensitive skin, PCA Skin offers a separate Retinol Treatment for Sensitive Skin which may be a better starting point.

Yes. The retinol promotes cell turnover to help fade existing discolouration, while niacinamide works to reduce age-related skin yellowing and redness. Over time, users typically see a more even, brighter and clearer complexion.

No. This product contains 0.5% retinol (vitamin A), which is not recommended for use during pregnancy or breastfeeding. Please discontinue use if you become pregnant and consult your healthcare provider for pregnancy-safe alternatives.