Gluconolactone (PHA)

Our Gluconolactone (PHA) collection brings together serums, cleansers, moisturisers and tinted formulas containing the gentlest member of the hydroxy acid family. Featuring Medik8, SkinCeuticals, PRIORI, Exuviance, Neostrata and more, it is a go-to edit for anyone who wants smoother, brighter-looking skin without the sting.

Polyhydroxy acids have a larger molecular structure than glycolic or lactic acid, so they work more slowly on the skin's surface, loosening dead cells for a refined texture with less risk of sensitivity. Gluconolactone is also a humectant, drawing water into the skin, so it hydrates while it exfoliates. That makes it particularly appealing for sensitive, dry or mature skin, and for anyone new to acids. Neostrata and Exuviance were pioneers of PHA, and it remains a signature of their formulas.

Exuviance Gentle Cream Cleanser and Exuviance Night Corrector show how softly it can work, while Medik8 Press & Glow and Sleep Glycolic combine it with other acids for a brighter morning complexion. In the antioxidant category, SkinCeuticals C E Ferulic and SkinCeuticals P-TIOX feature it as a supporting player, and PRIORI LCA fx121 Skin Renewal Serum uses it to help refine the look of uneven texture. With so much choice, a Gluconolactone (PHA) product can be found for almost any step in a routine.

Becci, a registered aesthetics nurse with over two decades in specialist skincare and medical aesthetics, chooses each product here and loves helping customers start gently with exfoliation. Browse the Gluconolactone (PHA) edit, compare cleansers and serums, and contact us for honest, personal advice.