ZO Skin Health Radical Night Repair - Almost Perfect (Short-Dated 09/2026) 60ml retinol treatment for skin renewal.

ZO Skin Health Radical Night Repair - Almost Perfect (Short-Dated 09/2026) creamy texture swatch on a white background.

ZO Skin Health Radical Night Retinol

Name: ZO Skin Health Radical Night Retinol
Brand: ZO Skin Health
Price: 135.00 GBP
Availability: InStock

£135.00

Tax included.

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Consultation required

To purchase ZO Skin Health products, a telephone,video or in-clinic consultation with one of our skincare specialist nurses is required. You can either book your consultation below before completing the registration, or complete the online registration first — if approved, you can then then arrange your consultation, which you can do via WhatsApp or by calling 07811446686. If you need any help, call us on 07811446686 or message us on WhatsApp.

✓ 1% Encapsulated Retinol | ✓ Antioxidant Vitamins A, C and E | ✓ Soothing Sichuan Pepper Complex

ZO Skin Health Radical Night Retinol (previously Radical Night Repair) is ZO's highest-strength night retinol: a 1% encapsulated retinol formulated to help improve the appearance of skin texture, uneven tone and fine lines and wrinkles. Wrapped in antioxidant vitamins and a calming botanical complex, it is the 1% retinol for experienced vitamin A users who want visibly brighter, smoother, more even-looking skin.

The 1% encapsulated retinol in ZO Skin Health Radical Night Retinol diminishes the appearance of fine lines and wrinkles while improving skin smoothness, and the encapsulation, in sweet almond oleosomes within a silky base, helps meter its release through the night. Vitamins C, E and A provide additional antioxidant protection, and ZO's edelweiss and marrubium vulgare plant stem cells add more. Because 1% retinol asks a lot of the skin, ZO pairs it with a soothing complex of sichuan pepper fruit extract, sunflower seed oil and rosemary leaf extract that minimises the appearance of redness, while glycerin, sunflower and plukenetia volubilis (sacha inchi) seed oils hydrate and support the barrier with essential lipids.

Visible Results Users Love

Visibly brighter, more even-looking skin tone
Smoother texture and softer-looking fine lines and wrinkles
Calmer-looking skin thanks to the soothing botanical complex
Firmer, more resilient-feeling skin over time
Deep overnight nourishment from lipid-rich oils

Why This Beats a Standard Retinol Night Cream

1% encapsulated retinol - ZO Skin Health Radical Night Retinol is the strongest retinol in ZO's range, metered for comfort
Antioxidant vitamins A, C and E are built in alongside plant stem cells
A dedicated soothing complex addresses the redness that high-strength retinol can provoke
Lipid-rich oils hydrate and support the barrier, so skin is not left stripped
A silky, fast-absorbing texture that layers neatly under a ZO hydrator

Best For

Experienced retinol users ready for 1%
Uneven tone and dullness
Fine lines, wrinkles and rough texture
Skin that has plateaued on a lower-strength retinol
Anyone who wants a single, powerful evening step

Choose ZO Skin Health Radical Night Retinol once a lower-strength ZO retinol no longer challenges your skin; if you are newer to vitamin A, Retinol Skin Brightener 0.25% or Wrinkle + Texture is the kinder place to start.

With over 20 years in specialist skincare and medical aesthetics as a registered aesthetics nurse, Becci is cautious about 1% retinols and says so to clients who ask. Her honest advice is that most people do not need one - but for the experienced user who does, ZO Skin Health Radical Night Retinol is the one she recommends, because ZO has thought about the redness and dryness as carefully as the retinol.

Size: 60ml

FAQS

Is ZO Skin Health Radical Night Retinol the same as Radical Night Repair? +

Yes. ZO has renamed Radical Night Repair as Radical Night Retinol on its UK and US sites; it is the same 60ml 1% encapsulated retinol with the same antioxidant vitamins and soothing sichuan pepper complex. ZO has not published a formula statement alongside the new name, so go by the ingredient list on your pack.

Is ZO Skin Health Radical Night Retinol suitable for retinol beginners? +

No. ZO describes it as a high-potency retinol and asks anyone who has not used retinol to begin gradually; we would go further and suggest finishing a tube of Retinol Skin Brightener 0.5% or Wrinkle + Texture first. It is the strongest retinol in the ZO range.

How often should I use it? +

Following cleansing, apply to clean, dry skin twice a week, increase to alternate evenings, then every evening as tolerated. Pair it with a ZO functional hydrator to minimise anticipated reactions and wear SPF 30 or higher every day.

What is the difference between Radical Night Retinol and Wrinkle + Texture? +

Radical Night Retinol is a 1% encapsulated retinol with antioxidant vitamins and a soothing complex, aimed at experienced users. Wrinkle + Texture is a 0.5% microemulsion retinol with ZCORE and ZPRO complexes for firmness and hydration, and the step most people take before it.

Do I need a moisturiser on top? +

ZO recommends pairing every retinol with one of its functional hydrators - Hydrating Crème, Recovery Crème or Renewal Crème - to minimise anticipated reactions. The formula itself is lipid-rich, so very oily skin may only need the hydrator on dry patches.

Does it contain fragrance? +

Yes - the ingredient list includes fragrance (parfum) with citral and limonene. If your skin reacts to fragranced products, patch test before using it across the whole face.

Why is my skin red and flaky after starting it? +

Redness, flakiness, dryness, burning or stinging are what ZO calls anticipated reactions when starting a retinol, and with a 1% strength they are more likely. Drop back to twice a week, use a ZO hydrator, and build up again once skin settles; with regular use it acclimatises.

Can I use it with vitamin C or exfoliating acids? +

Keep vitamin C for the morning and this retinol for the evening. Exfoliating acids, scrubs and peels should go on separate evenings from a 1% retinol - and on the first weeks, consider pausing them altogether while skin adjusts.

Can I use ZO Skin Health Radical Night Retinol during pregnancy or while breastfeeding? +

ZO says it does not test its products on women who are pregnant or breastfeeding and asks customers to review the full ingredient list with their doctor or midwife before use. Because this product contains retinol, and most clinicians advise avoiding vitamin A during pregnancy and breastfeeding, we suggest pausing it for this time. Growth Factor Serum is ZO's retinol-free option for lines and texture during this time.